Personal protective equipment (PPE) is a frontline defense against infectious agents, but its effectiveness hinges on the correct order of donning (putting on) and doffing (taking off). Errors in sequence can lead to contamination, exposing healthcare workers and patients to pathogens.

The correct donning order begins with hand hygiene. Wash or sanitize hands thoroughly before touching any PPE. Next, put on the gown, ensuring it covers the torso fully. Then, apply a surgical or N95 respirator, sealing it around the nose and mouth. Goggles or a face shield follow, protecting the eyes from splashes. Finally, gloves are worn last, covering the cuffs of the gown to create a continuous barrier.

Doffing demands even greater caution. Gloves are removed first, using the glove-to-glove and skin-to-skin technique to avoid hand contamination. Then, goggles or face shield are taken off by handling only the straps. The gown is removed by peeling it away from the body, folding inward. The respirator is removed last, as it may trap airborne particles. Immediately perform hand hygiene after each removal step.

Why does order matter? PPE acts as a layered shield. Donning in the wrong order—like putting gloves before a gown—can leave gaps. Doffing incorrectly, such as removing the respirator first, can release trapped contaminants into the air. Training and practice are essential to master these sequences.

In outbreak settings, compliance with donning and doffing protocols reduces infection risk by up to 80%. Healthcare facilities must conduct regular drills and audits to reinforce these critical steps. Remember: proper PPE use is not just about wearing gear but wearing it in the right order.